Polypeptide Hormones Peptide Powder Gonadorelin 10mg

Cas No.: 71447-49-9; 33515-09-2

Gonadorelin Acetate Sequence: Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

Product Categories:Amino Acid Derivatives;Peptide;API;peptides

Gonadorelin Acetate Purity (HPLC): 98.0%min.

Gonadorelin Acetate Appearance: White powder

Gonadorelin Acetate Molecular Formula: C59H83N17O17

Gonadorelin Acetate Molecular Weight: 1302.39

Gonadorelin Acetate Single Impurity (HPLC): 0.5%max

Gonadorelin Acetate Amino Acid Composition: ±10% of theoretical

Gonadorelin Acetate Peptide Content (N%): ≥80.0% 

Water Content(Karl Fischer): ≤8.0%

Acetate Content(HPIC): ≤10.0%

Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)

MS (ESI): Consistent

Mass Balance: 95.0~105.0%

What is Gonadorelin ?

Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating  hormone and leutinizing hormone from the anterior pitutitary. 

GnRH is available as gonadorelin hydrochloride )and gonadorelin diacetate tetrahydrate for injectable  use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with 

cystic ovarian disease. 

Gonadorelin Application :

Gonadorelin is used to test how well the hypothalamus and the pituitary glands are working. It is also 

used to cause ovulation (release of an egg from the ovary) in women who do not have regular ovulation and menstrual periods because the hypothalamus gland does not release enough GnRH.

Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from 

the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process 

that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens.

The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a 

correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular 

growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its 

short half life requires infusion pumps for its clinical use.